斑馬魚是個高度再生的動物，科學家一直不知道斑馬魚如何感測失去組織量進而調整生長的速率。陳振輝與林耿慧實驗室聯手一起觀察斑馬失去部分尾巴後細胞集體遷移的現象，發現傷口位置的資訊是靠著集體遷移時產生的機械波傳遞到尾巴，失去越多組織，波就傳遞越遠，所以就越多細胞參與增生，加速增生的速度。
It has been mysterious how zebrafish senses the amount of tissue loss and adjusts its growth rate accordingly. We performed in toto imaging on the wound healing process after removing part of the tailfin and found that the information of wound position is propagated through mechanical waves generated during collective cell migration of epithelial cells. The more tailfin is lost, the longer the signal is propagated in the tailfin and thus more cells will be recruited to participate in the regrowth process for faster regrowth rate.
論文全文 Artical Link： https://www.nature.com/articles/s41567-023-02103-6
延伸閱讀 More Information： https://www.phys.sinica.edu.tw/index_detail.php?id=research&eng=T&newsid=1032